Mitotic apparatus is set of aster
, radial structures around
centriole pair, plus spindle fibers,
fibers extend across the
between the two pairs located
in cell poles. The
apparatus appears in and has
important in the orientation
gripping of chromosomes other
cellular elements them to
separate migrate to opposite
poles.

Substances that the formation
of mitotic apparatus, like ,
a molecule that to tubulin
molecules prevents the synthesis
microtubules, interrupt cell .
Colchicine is used study
chromosomes since paralyzes mitosis
when are condensed and
are more easily under the
microscope.